Editorial Commentary: Maximal Outcome Improvement: Another Arrow in the Quiver

Another arrow in the Drosophila quiver.

W accounts for the great popularity and success of Drosophila melanogaster as an experimental organism? There are many contributing practical reasons, including the relative ease with which large numbers can be grown at minimal expense, its having just four pairs of chromosomes, and the efficiency with which its organs and ornately patterned exterior can be examined. But there are two additiona...

Another arrow in the quiver--but at what cost?

Gamillscheg et al. report on a single patient who had a large pulmonary arteriovenous malformation with significant right-to-left shunting and a cerebrovascular accident secondary to presumed paradoxic embolism. The accompanying still-frame cineangiogram demonstrates a large arteriovenous malformation with a 10-mm feeding artery and no obvious narrowing, making it difficult to provide endovascu...

Smarter arrow now available in the food safety quiver.

Editorial Commentary

Socioeconomic status (SES) is a known risk factor for cardiovascular disease.1,2 However, unlike traditional Framingham risk factors, SES does not directly impact the cardiovascular system but exerts its cardiovascular effects via a complex interaction of biobehavioral factors, such as exercise and diet (Figure). Because these mediating behavioral factors are potentially modifiable, elucidating...

More than one arrow in the quiver: Why "100% renewables" misses the mark.

Jacobson et al. (1) aim to demonstrate that an allrenewable energy system is technically feasible. Not only are the study’s conclusions based on strong assumptions and key methodological oversights, but its framing also omits the essential notion of trade-offs. A far more relevant question is how renewable energy technologies relate to the broader set of options for meeting long-term societal g...